University of Wisconsin-Madison
Graduate Student, Chemical and Biological Engineering
Research Assistant
Thesis Title: Charge-modified high-performance tangential flow filtration (HPTFF) membranes for fractionation of therapeutic dairy proteins
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Mark R. Etzel
Regina M. Murphy |
About
Experimental evaluation of macroscopic system models and thermodynamic models for hindered transport of a charged solute through fluid filled charged pores of a tangential flow ultrafiltration membrane will be performed.
Based on model results, a system for fractionating serum proteins from milk serum and cheese whey will be designed using the productivity of membrane cascades and selectivity of charge modified systems, making UF attractive for bioprocessing.
In particular, alphalactalbumin will be fractionated from milk-serum microfiltration permeate and glycomacropeptide will be fractionated from cheese whey using novel tangential flow filtration membranes which have been modified using salt-tolerant polycations. An optimization study will be performed on the system to minimize the production cost and the system will be scaled-up for industrial scale production of these proteins.
Contact Information
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| Address: | Department of Chemical and Biological Engineering
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